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Time-varying nature of clinical risk factors for pancreatic cancer may aid earlier diagnosis

Body mass index, blood tests, comorbidities and medication use are temporally associated with cancer risk in the three years before a pancreatic cancer diagnosis.

OxCODE funding scheme awards 2022

Congratulations to Sarah Blagden, Skirmantas Kriaucionis and their collaborators who have been awarded funding in the third round of the OxCODE Funding Scheme.

Largest study to date confirms role of two hormones in aggressive prostate cancer risk

New, genetics and blood-based study links testosterone and insulin-like growth factor hormones to aggressive prostate cancer for the first time.

First DeLIVER study day

On Wednesday 8th June 2022, the DeLIVER consortium gathered for the first time to hear about the team’s progress towards the aim of detecting liver cancer earlier.

National clinical study launched to test new technologies for detecting liver cancer

The SELINA study will recruit patients with early liver cancers as part of the DeLIVER programme aiming to detect liver cancer earlier.

Early detection innovation award for Oxford researchers

Professor Julia Hippisley-Cox and Dr Tingting Zhu win funding for their collaborative project on novel test technologies for patient triage in primary care.

Greater adiposity linked to increased risk of fatal prostate cancer

A new Oxford study finds that greater body fat (adiposity) may increase the risk of dying from prostate cancer by up to 10%.

Predicting early recurrence of pancreatic cancer

Dr Daniel Hughes and colleagues identify NUDT15 as a potential biomarker for pancreatic cancer recurrence following surgery.

Funding to study stomach cancer development

Dr Francesco Boccellato receives a John Fell Fund award to investigate how the stomach lining changes shape during the transition from healthy tissue to cancer.

Automated assessment of pathology image quality

The new Oxford-developed artificial intelligence tool PathProfiler automates the quality control of large retrospective pathology image datasets to increase their usability in downstream research.

Oxford spin-out Optellum attains CE marking for its early lung cancer diagnosis AI technology

Optellum Virtual Nodule Clinic, including its proprietary artificial intelligence lung cancer prediction solution, has achieved CE certification under the European Union’s Medical Device Regulation.

Funding to develop a new device for breast cancer detection

Professor Jason Davis has been awarded a Cancer Research UK Early Detection and Diagnosis Primer Award to develop a single-step, ultra-sensitive device for detecting breast cancer cells in the blood.

A new opportunity for myeloma early diagnosis

Screening within a fracture clinic can expedite diagnoses of multiple myeloma and its precursor, MGUS.

Understanding AI-based lung nodule risk prediction

The contribution of individual features on clinical imaging scans to the performance of the LCP-CNN cancer risk prediction model developed in Oxford was investigated.

Blood tests provide no additional information to FIT alone when prioritising patients for colorectal cancer referral

Faecal immunochemical testing (FIT) alone leads to the identification of the same number of patients with colorectal cancer as more complicated approaches that combine the FIT result with the results of commonly used blood tests.

Adiposity in early life, but not adulthood, may protect against breast cancer

New data from the Million Women Study indicates that adiposity at different life stages is likely to affect the risk of postmenopausal breast cancer through distinct mechanisms.

First major UK prospective study for liver cancer underway

The Pearl clinical study will recruit 3000 patients with high-risk conditions for liver cancer with the aim of detecting liver cancer earlier as part of the Cancer Research UK-funded DeLIVER programme.

Comparing models to predict liver cancer in individuals with high-risk conditions

Members of the DeLIVER consortium and their collaborators have tested the performance of hepatocellular carcinoma risk prediction models in patients with cirrhosis and cured hepatitis C infection.

Groundbreaking University of Oxford research could lead to early diagnosis of pancreatic cancer

New research into the onset of diabetes which could go on to help in the early diagnosis of pancreatic cancer is being led by scientists at the University of Oxford.

Identifying protein biomarkers for pancreatic cancer

Dr Christiana Kartsonaki and colleagues from the China Kadoorie Biobank have identified several proteins in the blood that are associated with an increased risk of pancreatic cancer.

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